CAS 1219176-41-6 rac 3-(1,2,4-Triazol-1-yl)-L-alanine-[15N,d2]

General Information
Catalog: BLP-003981
CAS: 1219176-41-6
Molecular Formula: C5H6D2N3[15N]O2
Molecular Weight: 159.15

General Information

Catalog: BLP-003981

CAS: 1219176-41-6

Molecular Formula: C5H6D2N3[15N]O2

Molecular Weight: 159.15

Chemical Structure

Synonyms	rac 3-(1,2,4-Triazol-1-yl)-L-alanine 15N,D2
IUPAC Name	2-(15N)azanyl-3-(3,5-dideuterio-1,2,4-triazol-1-yl)propanoic acid
Related CAS	114419-45-3 (unlabelled)
Isomeric SMILES	[2H]C1=NN(C(=N1)[2H])CC(C(=O)O)[15NH2]
Canonical SMILES	C1=NN(C=N1)CC(C(=O)O)N
InChI	InChI=1S/C5H8N4O2/c6-4(5(10)11)1-9-3-7-2-8-9/h2-4H,1,6H2,(H,10,11)/i2D,3D,6+1
InChI Key	XVWFTOJHOHJIMQ-KEGBLKCBSA-N
Purity	>98%
Density	1.6±0.1 g/cm3
Storage	Store at 2-8°C

rac 3-(1,2,4-Triazol-1-yl)-L-alanine-[15N,d2], a specialized isotopically-labeled compound, holds myriad applications in scientific research. Here are key applications presented with high perplexity and burstiness:

Isotope Tracing in Metabolic Studies: Serving as a tracer in metabolic investigations, rac 3-(1,2,4-Triazol-1-yl)-L-alanine-[15N,d2] illuminates the intricate biochemical pathways and amino acid metabolism. The incorporation of isotopic labels, such as 15N and d2, allows researchers to monitor the assimilation and transformation of this compound within biological systems. This unravels the mysteries of metabolic flow and enzyme functions, fostering a deeper comprehension of cellular metabolism.

NMR Spectroscopy: With its isotopic labels, this compound is tailor-made for nuclear magnetic resonance (NMR) spectroscopy explorations. NMR spectroscopy serves as a potent tool for scrutinizing the structural dynamics and interactions of proteins and biomolecules. Introducing rac 3-(1,2,4-Triazol-1-yl)-L-alanine-[15N,d2] into samples enhances spectral resolution, unlocking detailed insights into molecular arrangements and conformational changes with finesse and precision.

Biochemical Assays: In the realm of biochemical studies, this compound proves valuable in enzyme activity assays that aim to investigate substrate interactions and conversions. Through the use of rac 3-(1,2,4-Triazol-1-yl)-L-alanine-[15N,d2], researchers can meticulously monitor and quantify enzyme kinetics and reaction mechanisms. This facilitates the identification of potential enzyme inhibitors or activators with promising therapeutic implications, pushing the boundaries of biochemical research.

Pharmacokinetics Studies: In the exploration of pharmacokinetics, rac 3-(1,2,4-Triazol-1-yl)-L-alanine-[15N,d2] emerges as a crucial tool for tracking drug metabolism and distribution in vivo. The precise isotopic labeling equips researchers to measure the compound's absorption, distribution, metabolism, and elimination phases with unmatched accuracy. These studies play a pivotal role in the development of safer and more efficacious therapeutic agents, propelling advancements in pharmacokinetics research and therapeutic innovation.