Rac-Glycerol-[1-13C]

Rac-Glycerol-[1-13C], a specialized labeled compound, finds applications in diverse scientific and medical research endeavors. Here are the key applications of Rac-Glycerol-[1-13C]:

Metabolic Flux Analysis: Embracing Rac-Glycerol-[1-13C] in metabolic flux analysis unveils insights into carbon pathways within cellular metabolism. By integrating this labeled glycerol into cells, researchers can scrutinize the distribution of the 13C label across various metabolic intermediates. This approach illuminates the dynamics of metabolic pathways, unveiling bottlenecks in biochemical processes with precision.

In Vivo Imaging: Harnessing Rac-Glycerol-[1-13C] alongside magnetic resonance spectroscopy (MRS) for in vivo imaging studies enables real-time tracking of metabolic processes within living organisms. The incorporation of the 13C label offers non-invasive avenues for studying disease progression and monitoring treatment effects in metabolic disorders. This technique holds particular significance in unveiling intricate disease mechanisms and treatment responses.

Lipid Metabolism Studies: Rac-Glycerol-[1-13C] serves as a cornerstone in lipid metabolism research by tracing the incorporation of labeled carbon into lipids. Scientists delve into how diverse cell types, such as adipocytes and hepatocytes, employ glycerol in synthesizing triglycerides and phospholipids. This exploration yields profound insights into metabolic afflictions like obesity and fatty liver diseases, shedding light on critical metabolic processes.

Enzyme Mechanism Elucidation: Unlocking the mysteries of enzyme mechanisms in glycerol metabolism becomes feasible with Rac-Glycerol-[1-13C]. By probing enzyme interactions with labeled glycerol, researchers unveil kinetic parameters and pinpoint key catalytic residues crucial for enzyme function. This mechanistic understanding underpins the design of enzyme inhibitors and engineered enzymes tailored for diverse industrial applications, showcasing the impact of molecular insights on bioengineering advancements.