Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-013983 |
Molecular Formula: C7H10D4N2O4S |
Molecular Weight: 226.28 |
Chemical Structure |
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Synonyms | (S)-Cystathionine-d4; Allocystathionine-d4; (2S)-2-amino-4-(2-amino-2-carboxyethyl)sulfanylbutanoic acid-d4; (2S)-2-Amino-4-((2-amino-2-carboxyethyl)thio)butanoic acid-d4; S-[(2-RS)-2-Amino-2-carboxyethyl)-L-homocysteine-3,3,4,4-d4 |
IUPAC Name | (2S)-2-amino-4-(2-amino-2-carboxyethyl)sulfanyl-3,3,4,4-tetradeuteriobutanoic acid |
Related CAS | 61949-06-2 (unlabelled) 535-34-2 (unlabelled DL-isomer) |
Purity | 95% by HPLC; 98% atom D |
Solubility | Soluble in Aqueous Acid (Slightly), Water (Slightly, Sonicated) |
Storage | Store at -20°C under inert atmosphere |
(S)-Cystathionine-[d4], a deuterium-labeled variant of the amino acid cystathionine, is frequently utilized as an internal standard in various research contexts. Here are the key applications:
Metabolomics Research: Delving into metabolomics, researchers often employ (S)-Cystathionine-[d4] to quantify cystathionine levels in biological samples through mass spectrometry. The deuterium labeling enables precise differentiation from endogenous cystathionine during analysis, facilitating insights into metabolic pathways and disease states associated with cystathionine metabolism.
Pharmacokinetic Studies: In pharmacokinetic investigations, researchers utilize (S)-Cystathionine-[d4] to monitor and measure the absorption, distribution, metabolism, and excretion (ADME) of cystathionine in biological systems. The stable isotope labeling provides accurate tracing without disrupting normal metabolic processes. This data is essential for drug development and comprehending biological responses to compounds.
Nutritional Studies: (S)-Cystathionine-[d4] is integrated into nutritional studies to explore how diet influences cystathionine metabolism. By incorporating the labeled compound into dietary interventions, researchers can track changes in cystathionine levels and metabolism. This investigation sheds light on the role of cystathionine in nutrition and its implications for health outcomes.
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