(S)-(-)-Verapamil-[d3] Hydrochloride

(S)-(-)-Verapamil-[d3] Hydrochloride, a deuterated variant of Verapamil, a potent calcium channel blocker, holds pivotal significance in both pharmacological and preclinical research. Here are the key applications of (S)-(-)-Verapamil-[d3] Hydrochloride:

Pharmacokinetic Studies: Delve into the realm of pharmacokinetic studies with (S)-(-)-Verapamil-[d3] Hydrochloride, a pivotal tool for exploring the absorption, distribution, metabolism, and excretion (ADME) of Verapamil. The precise deuterium labeling offers a unique vantage point for tracking the compound’s journey within biological systems, shedding light on the drug’s behavior and facilitating the optimization of dosage regimens.

Drug-Drug Interaction Studies: Uncover the intricate world of drug-drug interaction studies with (S)-(-)-Verapamil-[d3] Hydrochloride, a key player in evaluating the interplay between Verapamil and other medications. The deuterated form ensures a seamless mass spectrometric analysis of non-deuterated compounds, enabling the accurate measurement and assessment of how Verapamil influences or is influenced by co-administered drugs.

Metabolite Identification: Peer into metabolite identification studies with the aid of (S)-(-)-Verapamil-[d3] Hydrochloride, a valuable asset in distinguishing between the parent drug and its metabolites. The deuteration feature facilitates clear identification and quantification of metabolites through mass spectrometry, offering crucial insights into metabolic pathways and potential toxicological effects.

Mechanism of Action Research: Embark on a journey into the intricate world of mechanism of action research with (S)-(-)-Verapamil-[d3] Hydrochloride, a catalyst for unraveling the molecular intricacies of Verapamil’s mode of action. Leveraging the labeled compound, researchers can conduct detailed investigations into calcium channel interactions and other molecular targets, paving the way for the development of more efficacious cardiovascular therapies.