Inquiry List

* Name:
* Phone:
* Service & Products of Interested: [Labelled APIs] Sacubitril Calcium-[13C4]
Project Description:
* Quantity
* Email:
* Organization We recommend you to leave us your work email address so that we can serve you better. Please leave your organization information here if you don't have a work email address.
* Verification Code:

Our Highlights

Optimal Prices
Buying products on this site guarantees the best price
Flexible Batches
Flexible batch size to meet different needs of global customers
Prompt Delivery
Warehouses in multiple cities to ensure timely delivery
Quality Assurance
Strict process parameter control to ensure product quality
One-to-one Customization
One-to-one custom synthesis for special structural needs

Application Area

Environmental

Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.

Clinical diagnostic

In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.

Organic Chemistry

Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.

Metabolic Research

Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.

Sacubitril Calcium-[13C4]

Inquiry

General Information
Catalog: BLP-004184
Molecular Formula: C20[13C]4H28NO5.1/2Ca
Molecular Weight: 434.50

Chemical Structure

Description	Labelled Sacubitril. Sacubitril, also known as AHU377 or LCZ696, is an angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. LBQ657 inhibits the enzyme neprilysin, which is responsible for the degradation of atrial and brain natriuretic peptide, two blood pressure lowering peptides that work mainly by reducing blood volume.
Synonyms	[S-(R,S)]-[1,1'-Biphenyl]-4-pentanoic Acid,γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl-Ethyl Ester-13C4 Calcium
Related CAS	1369773-39-6 (unlabelled) 149709-62-6 (unlabelled free acid)
Canonical SMILES	CCOC(=O)C(C)CC(CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)O.[Ca]
InChI	InChI=1S/C24H29NO5.Ca/c1-3-30-24(29)17(2)15-21(25-22(26)13-14-23(27)28)16-18-9-11-20(12-10-18)19-7-5-4-6-8-19;/h4-12,17,21H,3,13-16H2,1-2H3,(H,25,26)(H,27,28);/t17-,21+;/m1./s1/i13+1,14+1,22+1,23+1;
InChI Key	SLERTBUHPREHKD-XIKWNFOHSA-N
Purity	99% by HPLC; 99% atom 13C
Appearance	Off-white Solid