Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-009142 |
CAS: 1219799-29-7 |
Molecular Formula: C13H5D4Cl3N2O |
Molecular Weight: 319.61 |
Chemical Structure |
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Description | An isotope labelled form of Triclocarban. Triclocarban is an antibacterial agent common in personal care products. |
Synonyms | 3,4,4'-Trichlorocarbanilide-d4; 3,4,4'-Trichlorodiphenylurea-d4; 1-(4-Chlorophenyl)-3-(3,4-dichlorophenyl)urea-d4 |
Related CAS | 101-20-2 (unlabelled) |
Melting Point | 254-256°C |
Purity | 95% by HPLC; 98% atom D |
Appearance | White Solid |
Storage | Store at -20°C |
Triclocarban-[d4], a deuterated variant of the antibacterial agent triclocarban, is primarily harnessed in research environments for its stability and traceability. Here are the key applications of Triclocarban-[d4]:
Pharmacokinetic Studies: Employing Triclocarban-[d4] in pharmacokinetic investigations allows for a comprehensive exploration of the absorption, distribution, metabolism, and excretion of triclocarban in the body. Its deuterated composition enables precise tracking via mass spectrometry, aiding in the delineation of optimal dosage regimens and ensuring the safety of pharmaceutical interventions.
Environmental Impact Research: Triclocarban-[d4] serves as a pivotal tool for examining the environmental destiny and movement of triclocarban across diverse ecological systems. By introducing the labeled compound into environmental samples, researchers can monitor its degradation and persistence, contributing crucial insights into the potential ecological risks posed by triclocarban to wildlife and ecosystems.
Analytical Chemistry: Within the realm of analytical chemistry, Triclocarban-[d4] acts as a fundamental internal standard for quantifying triclocarban levels in intricate matrices, such as biological fluids and environmental specimens. Its consistent chemical behavior compared to the non-labeled variant ensures precise and dependable measurements, facilitating the evaluation of contamination levels and adherence to health regulations.
Toxicological Research: In the domain of toxicological inquiries, Triclocarban-[d4] is a critical asset for assessing the safety and biological effects of triclocarban on human health. By utilizing the deuterated compound, researchers can discern triclocarban from its metabolites and other compounds in biological assessments. Such studies play a pivotal role in unraveling the potential health ramifications of triclocarban exposure, thereby guiding informed regulatory decisions and policy implementations.
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