Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-001613 |
CAS: 202656-13-1 |
Molecular Formula: C4D11NO3 |
Molecular Weight: 132.20 |
Chemical Structure |
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Synonyms | Tris(hydroxymethyl-d3)amino-d2-methane; Tris-d11 |
IUPAC Name | N,N,1,1,3,3-hexadeuterio-1,3-dideuteriooxy-2-[dideuterio(deuteriooxy)methyl]propan-2-amine |
Related CAS | 77-86-1 (unlabelled) |
Isomeric SMILES | [2H]C([2H])(C(C([2H])([2H])O[2H])(C([2H])([2H])O[2H])N([2H])[2H])O[2H] |
Canonical SMILES | C(C(CO)(CO)N)O |
InChI | InChI=1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2/i1D2,2D2,3D2,6D,7D,8D/hD2 |
InChI Key | LENZDBCJOHFCAS-RNVFPDRBSA-N |
Boiling Point | 219-220 °C at 10 mmHg(lit.) |
Melting Point | 162-165 °C(lit.) |
Purity | 98% atom D |
Density | 1.137 g/mL at 25 °C |
Tris-[d11] is a deuterium-labeled chemical compound often utilized in scientific research for its reliable isotopic tracing capabilities. Here are some key applications of Tris-[d11]:
Nuclear Magnetic Resonance (NMR) Spectroscopy: Tris-[d11] is widely used in NMR spectroscopy to study molecular structures and dynamics. The deuterium labeling provides a clear spectral signature that aids in the identification and quantification of chemical shifts. Researchers often use it to gain detailed insights into reaction mechanisms and molecular interactions.
Mass Spectrometry: In mass spectrometry, Tris-[d11] serves as an internal standard due to its distinct isotopic mass. It helps ensure accurate and precise quantification of analytes by compensating for variability in sample preparation and instrument response. This makes it particularly useful in complex mixture analysis where precision is crucial.
Pharmacokinetic Studies: Tris-[d11] is employed in pharmacokinetic studies to trace and quantify the absorption, distribution, metabolism, and excretion of drugs. Its deuterated nature allows for minimal interference with biological processes while providing reliable tracking in metabolic pathways. This enhances the understanding of drug behavior and bioavailability in vivo.
Environmental Analysis: In environmental science, Tris-[d11] is used to study pollutant pathways and degradation processes. Its stable isotopic signature enables researchers to trace the movement and transformation of contaminants in various ecosystems. This application is vital for developing effective environmental management and remediation strategies.
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