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Vitamin E-[d6] (R,R,R) acetate

General Information
Catalog: BLP-008183
Molecular Formula: C31H46D6O3
Molecular Weight: 478.78
Chemical Structure
Vitamin E-[d6] (R,R,R) acetate
Description An isotope labelled derivative of Vitamin E. Vitamin E has many biological functions, including its role as a fat-soluble antioxidant.
Synonyms (R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl acetate-D6; (2R,4'R,8'R)-alpha-Tocopherol acetate-D6; (2R,4'R,8'R)-O-acetyl-5-methyl-7,8-bis(trideuteromethyl)tocol; (S)-2,7-dimethyl-5,8-bis(trideuteromethyl)-2-((4S,8S)-4,8,12-trimethyltridecyl)chroman-6-yl acetate
Related CAS 59-02-9 (unlabelled free base) 58-95-7 (unlabelled)
Purity 98% by HPLC; 93% atom D

Vitamin E-[d6] (R,R,R) acetate, a deuterated form of Vitamin E with unique labeling properties, finds diverse applications in scientific endeavors. Here are the key applications of Vitamin E-[d6] (R,R,R) acetate:

Nutritional Studies: Exploring the metabolism and bioavailability of Vitamin E, researchers employ Vitamin E-[d6] (R,R,R) acetate as a tool in unraveling the intricate pathways of Vitamin E within the human body. By utilizing this deuterated variant, scientists can meticulously track the absorption, distribution, and excretion of Vitamin E, shedding light on its precise role in human health and nutrition.

Pharmacokinetic Studies: In the realm of pharmacokinetics, the deuterated form of Vitamin E serves as a valuable asset, enabling in-depth investigations into the dynamics of Vitamin E-based medications. By analyzing the labeled acetate, researchers can gather detailed insights into the absorption rate, bio-distribution, metabolism, and elimination of the drug, providing essential data for the advancement and refinement of Vitamin E-derived pharmaceuticals.

Antioxidant Mechanism Research: Delving into the protective effects of Vitamin E, scientists utilize Vitamin E-[d6] (R,R,R) acetate to examine the intricate mechanisms of antioxidant activity. Through detailed analysis of the compound’s interactions with free radicals and reactive species, researchers unlock crucial insights into its safeguarding effects on cellular components, laying the foundation for the development of therapies targeting oxidative stress-related diseases.

Stable Isotope Labeling: Serving as a cornerstone in stable isotope labeling experiments, this compound plays a pivotal role in labeling biological molecules without compromising their physiological attributes. Through the lens of mass spectrometry and other analytical methodologies, the deuterated Vitamin E acetate aids in unraveling complex biological pathways and interactions involving Vitamin E, offering invaluable contributions to both fundamental and applied bioscience research.

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