Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-013266 |
Molecular Formula: C3[13C]2H12O5 |
Molecular Weight: 154.13 |
Chemical Structure |
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Description | Isotope labelled analogue of D-arabinitol, a sugar alcohol. D-arabinitol was used as a diagnostic tool for the detection of fungal infections in neutropenic patients. |
Synonyms | D-Arabitol-1,2-13C2; D-Lyxitol-1,2-13C2; D-[4,5-13C2]lyxitol; D-[1,2-13C2]arabinitol; D-Arabinitol-1,2-13C2 |
Related CAS | 488-82-4 (unlabelled) |
Melting Point | 102-105°C |
Purity | 98% by CP; 98% atom 13C |
Solubility | Soluble in DMSO, Methanol |
Appearance | White Solid |
Storage | Store at -20°C |
D-arabinitol-[1,2-13C2], a stable isotopic compound, finds utility across various research domains. Here are the key applications of this compound:
Metabolic Flux Analysis: Serving as a tracer in metabolic flux analysis, D-arabinitol-[1,2-13C2] illuminates central carbon metabolism. By tracing its incorporation into diverse metabolic intermediates, researchers unravel the intricate pathways and fluxes within different organisms. This insight is paramount for comprehending cellular metabolism and pinpointing targets for metabolic engineering.
Stable Isotope Labeling Studies: Widely employed in stable isotope labeling studies, D-arabinitol-[1,2-13C2] offers a window into metabolic transformations and interconversions. By integrating this labeled compound into biological systems, researchers trace biochemical pathways and delve into the dynamics of metabolic reactions. This methodology enriches our comprehension of intricate biological networks and metabolic regulation.
Enzyme Mechanism Studies: Researchers harness D-arabinitol-[1,2-13C2] to probe the mechanisms of enzymes pivotal in carbohydrate metabolism. Leveraging the labeled substrate, they unravel the enzymatic steps and intermediates involved in reactions catalyzed by critical enzymes like dehydrogenases and isomerases. This knowledge underpins the development of enzyme inhibitors and the refinement of enzymes for diverse industrial applications.
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