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D-arabinitol-[1,2-13C2]

General Information
Catalog: BLP-013266
Molecular Formula: C3[13C]2H12O5
Molecular Weight: 154.13
Chemical Structure
D-arabinitol-[1,2-13C2]
Description Isotope labelled analogue of D-arabinitol, a sugar alcohol. D-arabinitol was used as a diagnostic tool for the detection of fungal infections in neutropenic patients.
Synonyms D-Arabitol-1,2-13C2; D-Lyxitol-1,2-13C2; D-[4,5-13C2]lyxitol; D-[1,2-13C2]arabinitol; D-Arabinitol-1,2-13C2
Related CAS 488-82-4 (unlabelled)
Melting Point 102-105°C
Purity 98% by CP; 98% atom 13C
Solubility Soluble in DMSO, Methanol
Appearance White Solid
Storage Store at -20°C

D-arabinitol-[1,2-13C2], a stable isotopic compound, finds utility across various research domains. Here are the key applications of this compound:

Metabolic Flux Analysis: Serving as a tracer in metabolic flux analysis, D-arabinitol-[1,2-13C2] illuminates central carbon metabolism. By tracing its incorporation into diverse metabolic intermediates, researchers unravel the intricate pathways and fluxes within different organisms. This insight is paramount for comprehending cellular metabolism and pinpointing targets for metabolic engineering.

Stable Isotope Labeling Studies: Widely employed in stable isotope labeling studies, D-arabinitol-[1,2-13C2] offers a window into metabolic transformations and interconversions. By integrating this labeled compound into biological systems, researchers trace biochemical pathways and delve into the dynamics of metabolic reactions. This methodology enriches our comprehension of intricate biological networks and metabolic regulation.

Enzyme Mechanism Studies: Researchers harness D-arabinitol-[1,2-13C2] to probe the mechanisms of enzymes pivotal in carbohydrate metabolism. Leveraging the labeled substrate, they unravel the enzymatic steps and intermediates involved in reactions catalyzed by critical enzymes like dehydrogenases and isomerases. This knowledge underpins the development of enzyme inhibitors and the refinement of enzymes for diverse industrial applications.

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