Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-013269 |
Molecular Formula: C3[13C]2H10O5 |
Molecular Weight: 152.11 |
Chemical Structure |
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Description | One of the labelled D-Lyxose. D-Lyxose is the C'-2 epimer of D-xylose. It is used in molecular model calculations for drug binding and recognition studies related to aldose reductase. |
Synonyms | D-[1,2-13C2]lyxose; D-lyxose-1,2-13C2 |
Related CAS | 1114-34-7 (unlabelled) |
D-lyxose-[1,2-13C2], a synthetic isotope-labeled sugar, is extensively utilized in diverse scientific studies. Here are the key applications of D-lyxose-[1,2-13C2]:
Metabolic Flux Analysis: Delving into metabolic flux analysis, D-lyxose-[1,2-13C2] serves as a pivotal tool for tracing the intricate pathways of sugar metabolism within cells. By scrutinizing how the 13C label integrates into metabolic intermediates, researchers can quantify the velocities of metabolic reactions, offering profound insights into cellular metabolism and guiding the development of metabolic engineering strategies.
Structural Biology: In the realm of structural biology, D-lyxose-[1,2-13C2] finds its niche as a component integrated into glycoconjugates for structural studies utilizing nuclear magnetic resonance (NMR) spectroscopy. The addition of 13C labels elevates the resolution and precision of NMR signals, facilitating in-depth structural analysis crucial for unraveling the roles of sugars within biological molecules.
Glycomics Research: D-lyxose-[1,2-13C2] emerges as a valuable asset in the field of glycomics research, where it plays a key role in studying the synthesis and functions of complex carbohydrates. By monitoring the labeled sugar, researchers delve into carbohydrate processing and modifications across diverse biological systems, shedding light on the functions of glycans in cell signaling and disease pathways.
Pharmaceutical Development: In the domain of pharmaceutical development, D-lyxose-[1,2-13C2] takes center stage by aiding in the exploration of how labeled sugars interact with biological targets to inform the creation of novel therapeutics. The isotopic labeling enables precise tracking of the sugar's behavior within biological systems, guiding the design of sugar-based medications and enhancing our understanding of their mechanisms of action—a critical step in advancing glycan-targeted therapies.
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