D-Mannose-[1,2,3-13C3]

D-Mannose-[1,2,3-13C3], a specialized mannose variant with isotopic labeling, boasts a myriad of applications in bioscience research. Here are the key applications of D-Mannose-[1,2,3-13C3]:

Metabolic Pathway Tracing: Unraveling the intricacies of metabolic pathways, D-Mannose-[1,2,3-13C3] assumes a critical role in tracing carbohydrate metabolism. By introducing this labeled sugar, researchers can meticulously monitor its journey into various metabolites using advanced techniques like NMR or mass spectrometry. This method enables precise mapping of metabolic flux, providing profound insights into mannose utilization within cellular systems.

Glycoprotein Research: In the realm of glycoprotein studies, D-Mannose-[1,2,3-13C3] emerges as a pivotal tool for deciphering the enigma of glycoprotein biosynthesis and turnover dynamics. Cultivating cells with this labeled mannose facilitates its integration into glycoprotein structures, allowing scientists to track and quantify the dynamic behavior of glycoproteins. This approach is paramount for unraveling protein glycosylation mechanisms and comprehending their pivotal roles in cell signaling pathways and disease progression.

Nutritional Studies: Addressing inquiries in nutrition science, D-Mannose-[1,2,3-13C3] emerges as a potent tool for investigating the absorption and metabolic fate of mannose in the human body. Researchers leverage this compound to explore how dietary mannose is metabolized and its impacts on various health markers. The insights gleaned from such studies play a pivotal role in formulating evidence-based dietary guidelines and shedding light on the physiological significance of mannose in human nutrition and well-being.