Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-013325 |
Molecular Formula: C5[13C]H10O6 |
Molecular Weight: 179.13 |
Chemical Structure |
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Description | D-glucono-1,5-lactone is the lactone derivative of D-gluconic acid. D-glucono-1,5-lactone is widely used as a food additive to approach a curing, pickling or leavening effect. |
Synonyms | D-[6-13C]glucono-1,5-lactone; D-[6-13C]gluconic acid delta-lactone |
Related CAS | 90-80-2 (unlabelled) |
D-glucono-1,5-lactone-[6-13C], a stable isotope-labeled compound, possesses unique properties that make it invaluable for a diverse range of research applications. Here are the key applications of D-glucono-1,5-lactone-[6-13C]:
Metabolic Flux Analysis: Employing D-glucono-1,5-lactone-[6-13C] in metabolic flux analysis enables researchers to intricately trace the intricate pathways of glucose metabolism. By integrating this isotopically labeled compound into biological systems, scientists can meticulously monitor its conversion and distribution within metabolic networks, shedding light on the dynamic nuances of metabolic pathways and uncovering potential rate-limiting steps.
NMR Spectroscopy: In the realm of nuclear magnetic resonance (NMR) spectroscopy, D-glucono-1,5-lactone-[6-13C] emerges as a pivotal tool for probing the structural and conformational dynamics of biomolecules. The incorporation of the 13C-labeled isotope enhances sensitivity and resolution in NMR experiments, facilitating in-depth exploration of molecular interactions and chemical environments through detailed analysis.
Biochemical Research: Delving into enzymatic reactions and their kinetics, D-glucono-1,5-lactone-[6-13C] plays a critical role in unraveling the intricate mechanisms governing enzyme action. Whether acting as a substrate or inhibitor, this compound aids in elucidating the specifics of enzyme specificity, catalytic efficiency, and regulatory mechanisms, offering researchers profound insights into the complex world of biochemical processes.
Medical Research: Extending its reach into medical research, this isotope-labeled compound proves instrumental in examining glucose metabolism in various disease contexts such as diabetes and cancer. By tracking the fate of D-glucono-1,5-lactone-[6-13C] within tissues and cells, scientists can pinpoint metabolic alterations associated with these conditions, paving the way for the development of innovative therapeutic approaches and diagnostic tools.
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