Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-009250 |
CAS: 83379-39-9 |
Molecular Formula: C4[13C]H10O5 |
Molecular Weight: 151.12 |
Chemical Structure |
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Description | One of the labelled D-Lyxose. D-Lyxose is the C'-2 epimer of D-xylose. It is used in molecular model calculations for drug binding and recognition studies related to aldose reductase. |
IUPAC Name | (2S,3S,4R)-2,3,4,5-tetrahydroxy(2-13C)pentanal |
Related CAS | 1114-34-7 (unlabelled) |
Canonical SMILES | C(C(C(C(C=O)O)O)O)O |
InChI | InChI=1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4-,5-/m1/s1/i3+1 |
InChI Key | PYMYPHUHKUWMLA-RYINFSMFSA-N |
D-Lyxose-[2-13C], a stable isotope-labeled sugar with unique carbon labeling, finds specific applications across various fields. Here are the key applications of D-Lyxose-[2-13C]:
Metabolic Flux Analysis: Delving into metabolic flux analysis, researchers employ D-Lyxose-[2-13C] to trace carbon pathways within biological systems. Through the integration of this labeled sugar into the metabolic network, scientists meticulously monitor its conversion into diverse metabolic products. This comprehensive analysis yields quantitative insights into carbon flow, shedding light on potential bottlenecks or inefficiencies present within metabolic pathways.
NMR Spectroscopy Studies: Widely utilized in nuclear magnetic resonance (NMR) spectroscopy, D-Lyxose-[2-13C] serves as a vital tool for studying the structure and dynamics of carbohydrates. The 13C label enables precise detection of the sugar's carbon atoms, facilitating in-depth structural analysis. This capability is instrumental for researchers investigating interactions between sugars and various biomolecules such as proteins and nucleic acids, enhancing our understanding of complex molecular dynamics.
Glycobiology Research: Within the realm of glycobiology, D-Lyxose-[2-13C] holds a pivotal role, particularly in the exploration of glycoproteins and glycolipids. This labeled sugar can be seamlessly incorporated into intricate carbohydrate structures, allowing detailed tracing and analysis of glycan moieties. Such investigations contribute to elucidating the roles of sugars in crucial cellular processes such as signaling, molecular recognition, and immune responses, broadening our comprehension of intricate biological mechanisms.
Biotechnology and Bioengineering: In the domain of biotechnology, D-Lyxose-[2-13C] is harnessed to optimize and engineer metabolic pathways for the synthesis of valuable biochemicals. By meticulously tracking carbon flow through engineered pathways, researchers can evaluate the efficiency of metabolic engineering strategies. This critical information plays a key role in the development of microbes or cell lines with enhanced production capacities for a diverse range of industrially significant compounds, spanning pharmaceuticals, biofuels, and beyond.
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