Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-012791 |
CAS: 75607-68-0 |
Molecular Formula: C6H13DO6 |
Molecular Weight: 183.18 |
Chemical Structure |
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Synonyms | D-Mannitol-2-C-d; Mannite-2-C-d; Osmitrol-2-C-d; Osmofundin-2-C-d; Cordycepic acid-2-C-d |
IUPAC Name | (2R,3R,4R,5R)-2-deuteriohexane-1,2,3,4,5,6-hexol |
Related CAS | 69-65-8 (unlabelled) |
Canonical SMILES | C(C(C(C(C(CO)O)O)O)O)O |
InChI | InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1/i3D |
InChI Key | FBPFZTCFMRRESA-JNHZOBAGSA-N |
Purity | ≥90% |
Solubility | Soluble in DMSO (Slightly), Water (Slightly) |
Appearance | White Solid |
Storage | Store at RT under inert atmosphere |
D-Mannitol-[2-C-d], a labeled derivative of mannitol, a versatile sugar alcohol extensively used in research and industrial applications, showcases a multitude of uses. Below are the key applications of D-Mannitol-[2-C-d]:
Isotope Tracing in Metabolism: Within the domain of metabolic investigations, D-Mannitol-[2-C-d] emerges as a valuable tracer, illuminating the intricate pathways of carbohydrate metabolism. By meticulously monitoring the labeled carbon, researchers embark on a journey to unveil the metabolic fate of mannitol across diverse organisms, ranging from humans to plants. This application is pivotal for unraveling the complexities of energy generation, storage, and utilization within cellular systems.
Drug Delivery Systems: Positioned at the forefront of pharmaceutical advancement, D-Mannitol-[2-C-d] assumes a central role in sophisticated drug delivery systems. Due to its biodegradable nature, mannitol often serves as a carrier molecule in pharmaceutical formulations, particularly in lyophilized preparations. The labeled variant, D-Mannitol-[2-C-d], facilitates real-time monitoring and in-depth analysis of drug distribution and release mechanisms, propelling the field of drug delivery into new realms of innovation.
Biomedical Imaging: At the convergence of D-Mannitol-[2-C-d] and state-of-the-art imaging technologies, such as Nuclear Magnetic Resonance (NMR) and Positron Emission Tomography (PET), a realm brimming with potential unfolds. The labeled compound enhances image contrast and clarity, enabling detailed exploration of physiological processes within living organisms. This application stands as a cornerstone in diagnostic imaging, enabling meticulous monitoring of disease progression and physiological changes with unparalleled precision.
Plant Physiology Studies: Delving into the intricate tapestry of plant biology, D-Mannitol-[2-C-d] emerges as a pivotal player in osmoregulation and stress response investigations. Plants often deploy mannitol as an osmoprotectant, and the labeled version aids researchers in tracing its movement and accumulation under diverse stress conditions, such as drought and high salinity. Through these studies, a profound understanding of plant resilience is attained, paving the way for the development of genetically and agronomically fortified crop varieties.
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