D-Mannose-[13C6]

D-Mannose-[13C6], a stable isotopically labeled variant of D-Mannose, holds immense value in a multitude of research and diagnostic realms. Here are the key applications of D-Mannose-[13C6]:

Metabolic Flux Analysis: Delving into the intricacies of metabolic flux, D-Mannose-[13C6] emerges as an indispensable tool for unraveling the labyrinthine pathways of carbohydrate metabolism within cells. By integrating this specially labeled sugar into metabolic processes, researchers can meticulously track the distribution and conversion of glucose derivatives, shedding light on cellular metabolic landscapes and aiding in the comprehension of disorders linked to carbohydrate metabolism.

Glycoprotein Studies: In the captivating realm of glycoprotein exploration, D-Mannose-[13C6] takes center stage, offering insights into the synthesis and modification pathways of these complex biomolecules. By monitoring the incorporation of labeled mannose into glycoproteins, scientists can delve into the dynamic world of glycosylation processes—a crucial endeavor in fields like immunology and cancer research, where glycoproteins wield significant influence.

NMR Spectroscopy: The realm of Nuclear Magnetic Resonance (NMR) spectroscopy finds a stalwart ally in D-Mannose-[13C6], particularly when exploring carbohydrate structures and interactions. The isotopic labeling elevates NMR signals, enabling a meticulous analysis of molecular conformations and dynamics. This aids in the intricate task of unraveling the structures of complex biomolecules and advancing the design of pharmaceutically relevant compounds.

Microbial Pathogenesis: Peering into the enigmatic domain of microbial pathogenesis, researchers turn to D-Mannose-[13C6] to unravel the role of mannose in microbial adhesion and the subsequent onset of pathogenicity. Pathogens like E. coli cling to mannose residues on host cells as a pivotal step in the infection process. By harnessing the power of labeled mannose, scientists delve into the intricate dance of these interactions, striving to devise innovative strategies for thwarting infections before they take hold.