Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-013329 |
Molecular Formula: [13C]6H12O6 |
Molecular Weight: 186.11 |
Chemical Structure |
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Description | D-Altrose is the epimer of D-glucose at C3 and have recently been discovered to possess antioxidant properties by the suppression of reactive oxygen species production in mitochondria due to competition with D-glucose at the cellular level. |
Synonyms | D-[UL-13C6]altrose; D-altrose-U-13C6 |
Related CAS | 1990-29-0 (unlabelled) |
D-altrose-[UL-13C6] is an isotopically labeled compound with diverse research applications in the biosciences:
Metabolic Flux Analysis: Delving into metabolic studies with D-altrose-[UL-13C6] unveils a meticulous dissection of carbon flow within metabolic pathways. By tracking the incorporation of [13C], profound insights into cellular metabolism emerge, revealing the dynamic activity of specific pathways. This method proves invaluable in unraveling the complexities of diseases like cancer and diabetes, where metabolic dysregulation plays a pivotal role.
Stable Isotope Labeling: In the realms of proteomics and metabolomics, D-altrose-[UL-13C6] acts as a stable isotope label for precise quantification and analysis of biomolecules. Its role in distinguishing newly synthesized molecules from existing ones enables meticulous measurements and tracking of biochemical processes, offering a peek into cellular dynamics and molecular interactions across diverse biological systems.
Structural Biology: Employed in NMR and various spectroscopic studies, D-altrose-[UL-13C6] aids in unraveling the structure and dynamics of biomolecules. The uniform [13C] labeling generates distinct signals that support detailed mapping of molecular structures, essential for understanding the conformation and function of complex biological macromolecules. This breakthrough paves the way for advancements in the field of structural biology.
Biotechnology and Synthetic Biology: Positioned at the convergence of biotechnology and synthetic biology, D-altrose-[UL-13C6] plays a crucial role in engineering biological systems. By integrating labeled sugars into metabolic networks, researchers can efficiently monitor and optimize the production of desired compounds such as biofuels and pharmaceuticals. This pioneering approach is indispensable for driving advancements in industrial biotechnology processes and expanding the frontiers of synthetic biology applications.
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