β-D-Galp-(1,3)-D-GalpNAc-[UL-13C6]

β-D-Galp-(1,3)-D-GalpNAc-[UL-13C6] is a complex carbohydrate compound labeled with the carbon-13 isotope, offering unique opportunities in the field of biological and biochemical research. Here are some key applications of β-D-Galp-(1,3)-D-GalpNAc-[UL-13C6]:

Glycobiology Research: This isotopically labeled carbohydrate is invaluable in studying glycosylation patterns and glycan structures. Researchers can utilize it to trace metabolic pathways of glycans and understand their roles in cellular processes. Such information is crucial for elucidating the functions of glycans in health and disease.

Metabolic Flux Analysis: In metabolic studies, β-D-Galp-(1,3)-D-GalpNAc-[UL-13C6] can be used to track carbohydrate metabolism in living organisms. Incorporating this labeled compound into metabolic flux experiments allows for precise quantification of metabolic rates and pathway utilization. This is essential for understanding complex metabolic networks and engineering microbes for industrial applications.

NMR Spectroscopy: The carbon-13 label in β-D-Galp-(1,3)-D-GalpNAc-[UL-13C6] makes it an ideal candidate for nuclear magnetic resonance (NMR) spectroscopy studies. Researchers can obtain detailed insights into the structure, dynamics, and interactions of carbohydrates at an atomic level. This technique helps in the structural elucidation of complex glycoconjugates and their interactions with proteins.

Biomarker Discovery: β-D-Galp-(1,3)-D-GalpNAc-[UL-13C6] can be used in the discovery and validation of biomarkers for various diseases, including cancers and metabolic disorders. By studying the alterations in glycan structures and their metabolic pathways, researchers can identify potential diagnostic and prognostic biomarkers. Such biomarkers are crucial for early detection and personalized treatment strategies.