Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-009062 |
Molecular Formula: C5[13C]H14O6 |
Molecular Weight: 183.16 |
Chemical Structure |
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Description | Labelled L-mannitol for the preparation of L-fructose and D-sorbose. It can also be used to produce D-sucrose from Allitol by oxidation of the microbial strain Aerooerogenes IK7. |
Synonyms | L-Mannitol-1-13C; L-[1-13C]mannitol |
IUPAC Name | (2S,3S,4S,5S)-(1-13C)hexane-1,2,3,4,5,6-hexol |
Related CAS | 643-01-6 (unlabelled) |
Purity | 98% by CP; 99% atom 13C |
Storage | Store at 2-8°C |
L-Mannitol-[1-13C], a stable isotope-labeled compound, finds extensive applications in biomedical and biotechnological research. Here are the key applications of L-Mannitol-[1-13C]:
Metabolic Flux Analysis: Delving into metabolic studies, L-Mannitol-[1-13C] emerges as a pivotal tracer for probing carbohydrate metabolism. By meticulously monitoring the incorporation and conversion of the labeled carbon, researchers can unveil the intricate metabolic pathways and fluxes operating within cells and tissues. This profound insight aids in deciphering metabolic disorders and honing industrial fermentation processes to unparalleled precision.
NMR Spectroscopy: Embarking on a journey through Nuclear Magnetic Resonance (NMR) spectroscopy, L-Mannitol-[1-13C] stands as a beacon for exploring the structural and dynamic nuances of biological molecules. The insertion of the 13C label elevates the sensitivity and resolution of NMR experiments, presenting a window into the complex realm of carbohydrates and their interactions with other biomolecules, unlocking a treasure trove of information waiting to be unearthed.
Plant Physiology Research: Embracing the realm of plant sciences, L-Mannitol-[1-13C] emerges as a beacon illuminating the mysteries of carbohydrate transport and distribution within plant systems. By tracing the path of the labeled carbon, researchers embark on a voyage of discovery unraveling the intricacies of photosynthetic activities and the allocation of assimilates within plants. This knowledge forms the bedrock for understanding the growth, development, and response mechanisms of plants to environmental stresses, painting a vivid canvas of botanical wonders.
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