L-ribose-[1-13C], a carbon-13 labeled isotopic sugar molecule, finds diverse applications in research. Here are the key applications of L-ribose-[1-13C]:
Metabolic Flux Analysis: Utilizing L-ribose-[1-13C] as a tracer, researchers delve into metabolic pathways in cell biology. By integrating this labeled sugar into cellular systems, they can meticulously trace its integration and conversion across various metabolic processes. This data is pivotal for unraveling flux distributions, pathway regulations, and the intricate biochemical dynamics within cells.
NMR Spectroscopy: In the realm of NMR spectroscopy, L-ribose-[1-13C] emerges as a powerful tool for scrutinizing molecular structures and interactions. The presence of the carbon-13 isotope elevates the sensitivity and resolution of NMR signals, enabling in-depth structural analysis of complex biomolecules. Researchers can glean insights into molecular conformations, dynamics, and the surrounding environments of the labeled sugar with precision.
Isotopic Labeling in Drug Metabolism: Employing L-ribose-[1-13C] in pharmacokinetic studies sheds light on drug metabolism and excretion pathways. By tagging drugs with carbon-13, scientists can meticulously track metabolic conversions both in vivo and in vitro. This knowledge plays a vital role in comprehending the bioavailability and metabolic destiny of pharmaceuticals, which is essential for drug development and safety assessments.
Glycomics and Carbohydrate Research: In the domain of glycomics, L-ribose-[1-13C] serves as a valuable asset for exploring the structure-function relationships of carbohydrates. Researchers leverage this isotopically labeled sugar to probe glycosylation patterns, enzyme activities, and carbohydrate interactions. These studies deepen our understanding of the roles of sugars in cellular processes, shedding light on their implications in health and disease.
![L-ribose-[1-13C]](https://resource.bocsci.com/structure/l-1-13c-ribose.gif)
