Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-013388 |
Molecular Formula: [13C]6H12O6 |
Molecular Weight: 186.11 |
Chemical Structure |
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Description | L-mannose-[UL-13C6] is the labelled analogue of L-Mannose. L-Mannose is the isomer of D-Mannose. It is involved in N and O glycosylation of bovine. It is also used for the O-glycosylation of the T helper cell-derived cytokine interlukin-17A. |
Synonyms | L-[UL-13C6]mannose; L-mannose-U-13C6 |
Related CAS | 10030-80-5 (unlabelled) |
L-mannose-[UL-13C6], a specialized labeled monosaccharide, finds diverse applications in biochemical studies. Here are the key applications of L-mannose-[UL-13C6]:
Metabolic Flux Analysis: In the realm of metabolic flux analysis, L-mannose-[UL-13C6] serves as a pivotal tool for monitoring carbohydrate metabolism within cellular systems. Through its integration into cellular pathways, researchers can track its progression via mass spectrometry, shedding light on cellular responses under varying metabolic scenarios and unraveling the intricate metabolic networks at play.
Glycoprotein Biochemistry: Delving into the complexities of glycoprotein research, L-mannose-[UL-13C6] emerges as a crucial player in deciphering glycoprotein biosynthesis and modifications. When introduced into cell cultures, this labeled monosaccharide becomes part of glycan structures, enabling scientists to trace and analyze glycoprotein formations using cutting-edge isotopic labeling techniques. This application not only aids in the development of therapeutic glycoproteins but also enhances our understanding of disease-related glycosylation patterns.
Cellular Uptake Studies: At the forefront of cellular uptake investigations, L-mannose-[UL-13C6] serves as a powerful tool for unveiling the mechanisms behind mannose uptake in diverse cell types. By monitoring the uptake and metabolic utilization of this labeled sugar, researchers gain invaluable insights into the intricate transport systems specific to mannose and their regulatory mechanisms. This knowledge plays a critical role in unraveling the physiological and pathological functions of mannose within cellular environments.
Microbial Metabolism Research: Within the realm of microbial metabolism exploration, L-mannose-[UL-13C6] emerges as a key component for studying microbes that utilize mannose as a carbon source. By tracing the path of this labeled sugar through microbial metabolic pathways, scientists can uncover the metabolic capabilities and adaptability of microbes to varying environments. This knowledge not only enhances our understanding of microbial metabolism but also holds implications for optimizing microbial production processes in biotechnology applications, including the production of biochemicals and biofuels.
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