Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-009012 |
CAS: 1133229-29-4 |
Molecular Formula: C8H8D6N2O2 |
Molecular Weight: 176.25 |
Chemical Structure |
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Description | Levetiracetam-[d3] is an isotope labelled analog of Levetiracetam. Levetiracetam is a medication used to treat epilepsy. |
Synonyms | (αS)-α-(Ethyl-1,1,2,2,2-d5)-2-oxo-1-pyrrolidineacetamide-α-d; (-)-Levetiracetam-d6 |
IUPAC Name | 2,3,3,4,4,4-hexadeuterio-2-(2-oxopyrrolidin-1-yl)butanamide |
Related CAS | 102767-28-2 (unlabelled) |
Canonical SMILES | CCC(C(=O)N)N1CCCC1=O |
InChI | InChI=1S/C8H14N2O2/c1-2-6(8(9)12)10-5-3-4-7(10)11/h6H,2-5H2,1H3,(H2,9,12)/i1D3,2D2,6D |
InChI Key | HPHUVLMMVZITSG-CUYPRXAISA-N |
Melting Point | 116-117°C |
Purity | 98% by CP; 98% atom D |
Solubility | Soluble in Acetone, Chloroform, Methanol |
Appearance | White to Pale Yellow Solid |
Storage | Store at -20°C, Under inert atmosphere |
Levetiracetam-[2,3,3,4,4,4-butyramide-d6], a deuterated variant of the anticonvulsant Levetiracetam, finds primary utility in research settings. Explore its diverse applications:
Pharmacokinetic Studies: Delving into pharmacokinetics, Levetiracetam-[2,3,3,4,4,4-butyramide-d6] serves as a pivotal tool in unraveling the drug's absorption, distribution, metabolism, and excretion profiles. The deuterium labeling facilitates precise monitoring through mass spectrometry, furnishing crucial data to refine dosing strategies and enhance therapeutic outcomes.
Mechanistic Research: Researchers employ Levetiracetam-[2,3,3,4,4,4-butyramide-d6] to probe the intricate mechanisms underpinning its anticonvulsant properties. This compound aids in pinpointing the molecular targets and pathways essential for seizure management. Such profound insights pave the way for the development of advanced anticonvulsant agents with heightened safety margins.
Therapeutic Monitoring: Embracing therapeutic drug monitoring, Levetiracetam-[2,3,3,4,4,4-butyramide-d6] ensures patients attain optimal plasma concentrations for effective seizure management. Leveraging its unique labeling, precise measurement, and differentiation from endogenous metabolites are facilitated. This personalized approach fine-tunes treatment regimens, minimizing adverse effects, and maximizing therapeutic benefits.
Drug Interaction Studies: The deuterated rendition of Levetiracetam assumes a crucial role in probing potential drug interactions. By scrutinizing how concomitant medications modulate the pharmacokinetics of Levetiracetam-[2,3,3,4,4,4-butyramide-d6], researchers predict interactions that may impact drug efficacy or elevate toxicity risks. This valuable intelligence guides the formulation of safer medication combinations for individuals grappling with epilepsy.
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