Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-004350 |
Molecular Formula: C16H12D7NO |
Molecular Weight: 248.37 |
Chemical Structure |
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Description | Litoxetine-[d7] is a labelled Litoxetine, which is a selective serotonin reuptake inhibitor used as an antidepressant. |
Synonyms | Litoxetine D7; 4-(2-Naphthylmethoxy)piperidine d7; 4-(naphthalen-2-ylmethoxy)piperidine D7 |
Related CAS | 86811-09-8 (unlabelled) |
Purity | 98% by CP |
Litoxetine-[d7], a deuterated variant of the selective serotonin reuptake inhibitor (SSRI) Litoxetine, is primarily utilized in research environments. Here are key applications of Litoxetine-[d7] presented with high perplexity and burstiness:
Pharmacokinetic Studies: A cornerstone of pharmacokinetic research, Litoxetine-[d7] plays a pivotal role in delving into the absorption, distribution, metabolism, and excretion of Litoxetine within the human body. The deuterated iteration offers enhanced precision in tracking through mass spectrometry, courtesy of its unique isotopic label. This meticulous tracking aids researchers in unraveling the drug's behavioral patterns and fine-tuning dosing protocols for optimized outcomes.
Metabolism Research: Scientists harness Litoxetine-[d7] to delve deep into the metabolic pathways of Litoxetine by identifying its myriad metabolites. The deuterium labeling serves as a beacon, illuminating a clearer demarcation between the parent drug and its metabolites, thereby facilitating precise profiling. These studies serve as a cornerstone in comprehending the drug's metabolic stability and potential interactions, paving the way for advancements in pharmacological research.
Drug-Drug Interaction Studies: Embracing Litoxetine-[d7] for evaluating potential interactions with other pharmaceutical agents, researchers delve into how concurrent medications could impact Litoxetine's pharmacokinetic profile. The isotopically labeled Litoxetine-[d7] shines brightly in analytical measurements, enabling meticulous assessment of interactions with unparalleled accuracy.
Biological Mechanism Exploration: In the realm of SSRI mechanism research, Litoxetine-[d7] emerges as a key player in unraveling the intricate details of serotonin reuptake inhibition. Leveraging this intricately labeled compound, researchers navigate the labyrinth of serotonin's role in depression and anxiety, shedding light on the mode of action and refining our comprehension of these complex biological processes. This exploration fuels the development of cutting-edge antidepressant therapies, propelling the field towards more efficacious treatment modalities.
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