Name: Mepivacaine-[d3]
Brand: BOC Sciences
Rating: 5 (1 reviews)

General Information

Catalog: BLP-013044

CAS: 1346597-90-7

Molecular Formula: C15H19D3N2O

Molecular Weight: 249.37

Chemical Structure

Description	Mepivacaine-[d3] is the labelled analogue of Mepivacaine, which is an analgesic and anti-inflammatory agent.
Synonyms	Mepivacaine D3; N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide-d3; (±)-Mepivacaine-d3; 1-Methyl-2',6'-pipecoloxylidide-d3; APF 135-d3; Carbocain-d3; Carbocaine-d3; Carbocaine-V-d3; DL-Mepivacaine-d3; MepiSV-d3; Mepicaine-d3; Scandicain-d3; Scandicaine-d3; Tevacaine-d3
IUPAC Name	N-(2,6-dimethylphenyl)-1-(trideuteriomethyl)piperidine-2-carboxamide
Related CAS	96-88-8 (unlabelled) 1722-62-9 (unlabelled hydrochloride)
Canonical SMILES	CC1=C(C(=CC=C1)C)NC(=O)C2CCCCN2C
InChI	InChI=1S/C15H22N2O/c1-11-7-6-8-12(2)14(11)16-15(18)13-9-4-5-10-17(13)3/h6-8,13H,4-5,9-10H2,1-3H3,(H,16,18)/i3D3
InChI Key	INWLQCZOYSRPNW-HPRDVNIFSA-N
Melting Point	148-151°C
Purity	95% by HPLC; 98% atom D
Solubility	Soluble in Chloroform (Slightly), Methanol (Slightly)
Appearance	White to Pale Yellow Solid
Storage	Store at 2-8°C

Mepivacaine-[d3], a deuterated variant of the local anesthetic mepivacaine, finds widespread use in both preclinical and research environments. Here are the key applications of Mepivacaine-[d3]:

Pharmacokinetic Studies: Delving into the world of pharmacokinetics, Mepivacaine-[d3] serves as a valuable tool for exploring the absorption, distribution, metabolism, and excretion (ADME) of mepivacaine. The deuterated nature of this compound enables more precise tracing and differentiation within biological samples, aiding researchers in refining dosing strategies and enhancing safety profiles.

Metabolic Pathway Elucidation: By harnessing the power of Mepivacaine-[d3], scientists can unravel the intricate metabolic pathways and enzymatic transformations that govern its fate within the body. The incorporation of deuterium elevates the sensitivity of mass spectrometry for detecting metabolites, shedding light on how the drug undergoes processing and unveiling potential metabolites with therapeutic or toxic implications.

Analytical Method Development: The versatility of Mepivacaine-[d3] extends to the realm of analytical method development, playing a pivotal role in crafting and validating assays for drug analysis. Its stable isotope labeling facilitates the creation of highly sensitive and specific detection methods, crucial for clinical diagnostics and forensic investigations. This capability ensures the accurate quantification and monitoring of drugs in a variety of biological matrices, underpinning reliable results and insights.