CAS 1329799-64-5 Piracetam-[d8] - Isotope / BOC Sciences

General Information
Catalog: BLP-012522
CAS: 1329799-64-5
Molecular Formula: C6H2D8N2O2
Molecular Weight: 150.21

General Information

Catalog: BLP-012522

CAS: 1329799-64-5

Molecular Formula: C6H2D8N2O2

Molecular Weight: 150.21

Chemical Structure

Description	Piracetam-[d8] is the labelled analogue of Piracetam. Piracetam can be used mainly for myoclonus in UK.
Synonyms	Piracetam D8; 2-Oxo-1-pyrrolidineacetamide-d8; (2-Oxopyrrolidino)acetamide-d8; 2-(2-Oxopyrrolidin-1-yl)acetamide-d8; Avigilen-d8
IUPAC Name	2,2-dideuterio-2-(2,2,3,3,4,4-hexadeuterio-5-oxopyrrolidin-1-yl)acetamide
Related CAS	7491-74-9 (unlabelled)
Canonical SMILES	C1CC(=O)N(C1)CC(=O)N
InChI	InChI=1S/C6H10N2O2/c7-5(9)4-8-3-1-2-6(8)10/h1-4H2,(H2,7,9)/i1D2,2D2,3D2,4D2
InChI Key	GMZVRMREEHBGGF-SVYQBANQSA-N
Melting Point	137-140°C
Purity	98% by HPLC; 99% atom D
Solubility	Soluble in DMSO, Methanol
Appearance	White to Off-white Solid
Storage	Store at -20°C

Piracetam-[d8], a deuterated variant of Piracetam known for its potent cognitive enhancement properties, offers a sophisticated tool for both cognitive enhancement and neurological exploration. Here are the key applications of Piracetam-[d8]:

Pharmacokinetic Studies: By employing Piracetam-[d8] in pharmacokinetic investigations, researchers can meticulously track the drug's absorption, distribution, metabolism, and excretion pathways within the body. The deuterium labeling provides a distinct separation between the administered drug and endogenous metabolites, offering researchers precise insights into how the drug interacts within the complex systems of the body.

Neuropharmacology Research: In the expansive field of neuropharmacology, Piracetam-[d8] emerges as a pivotal tool for unraveling the intricate mechanisms through which nootropic drugs influence cognitive functions and neurological pathways. The stable isotope labeling enables researchers to isolate the specific effects of Piracetam from naturally occurring brain substances, leading to a profound understanding of how Piracetam enhances cognitive performance and modulates brain activities in a nuanced and profound manner.

Biotransformation Studies: Delving into biotransformation studies, the utilization of Piracetam-[d8] sheds light on the metabolic pathways and transformation products of Piracetam. By tracing the deuterated form, researchers can pinpoint the enzymes and metabolic routes involved in drug metabolism, providing essential insights for refining dosing regimens and mitigating potential side effects in a comprehensive and detailed manner.

Drug Interaction Research: Within the realm of drug interaction analysis, Piracetam-[d8] emerges as a key player in elucidating the complexities of how Piracetam interacts with other medications. By harnessing the labeled compound, scientists can explore these interactions without the interference of naturally occurring metabolites, enabling the identification of potential adverse interactions and ensuring the safety and efficacy of combined drug therapies with a meticulous and thorough approach.