Rabeprazole-[13C,d3] Sodium salt - Isotope / BOC Sciences

General Information
Catalog: BLP-004478
Molecular Formula: C17[13C]H17D3N3NaO3S
Molecular Weight: 385.44

General Information

Catalog: BLP-004478

Molecular Formula: C17[13C]H17D3N3NaO3S

Molecular Weight: 385.44

Chemical Structure

Catalog Number	Size	Price	Stock	Quantity
BLP-004478	5 mg	$1380	In stock

Catalog Number

Size

Price

Stock

Quantity

BLP-004478

5 mg

$1380

In stock

Description	Rabeprazole-[13C,d3] Sodium salt, is the labelled analogue of Rabeprazole, which is a medication that decreases stomach acid. Rabeprazole is a proton pump inhibitor used to suppress gastric acid production.
Synonyms	Rabeprazole 13C D3 Sodium salt; 2-[[[(4-(3-Methoxy-13C,d3)propoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole Sodium Salt
IUPAC Name	sodium;2-[[3-methyl-4-[3-(trideuterio(13C)methoxy)propoxy]pyridin-2-yl]methylsulfinyl]benzimidazol-1-ide
Related CAS	117976-90-6 (unlabelled) 1261392-48-6 (free base)
Canonical SMILES	CC1=C(C=CN=C1CS(=O)C2=NC3=CC=CC=C3[N-]2)OCCCOC.[Na+]
InChI	InChI=1S/C18H20N3O3S.Na/c1-13-16(19-9-8-17(13)24-11-5-10-23-2)12-25(22)18-20-14-6-3-4-7-15(14)21-18;/h3-4,6-9H,5,10-12H2,1-2H3;/q-1;+1/i2+1D3;
InChI Key	KRCQSTCYZUOBHN-CMOUKOEPSA-N
Purity	95% by CP; 98% atom D; 98% atom 13C
Solubility	Soluble in DMSO, Methanol
Storage	Store at-20°C

Rabeprazole-[13C,d3] Sodium salt is a labeled compound used in various research and preclinical settings. Here are some key applications ofRabeprazole-[13C,d3] Sodium salt:

Pharmacokinetic Studies:Rabeprazole-[13C,d3] Sodium salt is used in pharmacokinetic studies to track the absorption, distribution, metabolism, and excretion of rabeprazole in the body. The isotopic labeling allows for precise quantification using mass spectrometry. This data is crucial for understanding the drug’s bioavailability and optimizing dosing regimens.

Drug Metabolism Research: This compound is employed to investigate the metabolic pathways and mechanisms of rabeprazole metabolism. By usingRabeprazole-[13C,d3] Sodium salt, researchers can distinguish between the drug and its metabolites in complex biological matrices. This helps in identifying key metabolic enzymes and potential drug-drug interactions.

Bioequivalence Studies: In bioequivalence studies,Rabeprazole-[13C,d3] Sodium salt is employed to compare the pharmacokinetics of generic and branded formulations of rabeprazole. The labeled compound provides a robust analytical tool to detect even minor differences in drug absorption and bioavailability. This helps in ensuring the efficacy and safety of generic drugs.