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Ritalinic acid-[d9] hydrochloride

General Information
Catalog: BLP-009693
CAS: 1276197-13-7
Molecular Formula: C13H3D9NO2·HCl
Molecular Weight: 264.8
Chemical Structure
Ritalinic acid-[d9] hydrochloride
Description An isotope labelled metabolite of Methylphenidate. Methylphenidate is a central nervous system stimulant that is used in the treatment of attention deficit hyperactivity disorder and narcolepsy.
Synonyms Ritalinic-d9 Acid HCl; α-Phenyl-2-piperidineacetic Acid HCl
Related CAS 19395-40-5 (unlabelled)
Purity 95% by HPLC; 98% atom D;

Ritalinic acid-[d9] hydrochloride, a labeled chemical compound with diverse applications in pharmaceutical and research fields, is a key player in several crucial areas. Here are the applications:

Pharmacokinetic Studies: Delving into the intricate world of pharmacokinetics, Ritalinic acid-[d9] hydrochloride takes center stage in exploring the absorption, distribution, metabolism, and excretion (ADME) of drugs, particularly those pertinent to ADHD treatment. This deuterium-labeled compound acts as an internal standard, facilitating precise measurement and analysis in mass spectrometry. Such meticulous study is paramount in unraveling the drug’s behavior in the human body and fine-tuning dosing regimens for optimal therapeutic outcomes.

Metabolic Research: In the realm of metabolic research, Ritalinic acid-[d9] hydrochloride emerges as a vital tool for dissecting the complex metabolic pathways of methylphenidate, the active ingredient in Ritalin. Researchers harness the power of this labeled compound to meticulously trace and quantify the metabolites generated during drug metabolism. This detailed analysis aids in identifying metabolic pathways and shedding light on potential side effects or interactions with other medications, paving the way for safer and more informed drug usage.

Drug Development: At the forefront of drug development, Ritalinic acid-[d9] hydrochloride plays a pivotal role in shaping the landscape of new ADHD medications. This labeled compound serves as a cornerstone in evaluating the pharmacological profiles and effectiveness of emerging drug candidates. Such in-depth scrutiny is indispensable for crafting therapeutic agents that are not only more potent but also safer, heralding a new era of precision medicine.

Toxicology Studies: In the realm of toxicology, Ritalinic acid-[d9] hydrochloride stands as a guardian of safety, entrusted with assessing the potential toxicity and safeguarding the well-being of individuals using drugs related to methylphenidate. This compound serves as a vigilant sentinel, monitoring drug levels and metabolites in biological samples to ensure that the drug’s pharmacokinetics abide by safe boundaries. Such meticulous oversight contributes significantly to the comprehensive safety evaluation of novel pharmaceutical products, underscoring the importance of thorough toxicological assessments.

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