Name: Roxithromycin-[13C,d3]
Brand: BOC Sciences
Rating: 5 (1 reviews)

General Information

Catalog: BLP-004168

Molecular Formula: C40[13C]H73D3N2O15

Molecular Weight: 841.06

Chemical Structure

Description	Isotopic labelled Roxithromycin is a semi-synthetic macrolide antibiotic that inhibits bacterial cell growth and replication. It is used to treat respiratory tract, urinary and soft tissue infections.
IUPAC Name	(3R,4S,5S,6R,7R,9R,10Z,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-10-[2-(trideuterio(1-13C)methoxy)ethoxymethoxyimino]-oxacyclotetradecan-2-one
Related CAS	80214-83-1 (unlabelled)
Canonical SMILES	CCC1C(C(C(C(=NOCOCCOC)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)O)(C)O
InChI	InChI=1S/C41H76N2O15/c1-15-29-41(10,49)34(45)24(4)31(42-53-21-52-17-16-50-13)22(2)19-39(8,48)36(58-38-32(44)28(43(11)12)18-23(3)54-38)25(5)33(26(6)37(47)56-29)57-30-20-40(9,51-14)35(46)27(7)55-30/h22-30,32-36,38,44-46,48-49H,15-21H2,1-14H3/b42-31-/t22-,23-,24+,25+,26-,27+,28+,29-,30+,32-,33+,34-,35+,36-,38+,39-,40-,41-/m1/s1/i13+1D3
InChI Key	RXZBMPWDPOLZGW-FQMVUPGQSA-N
Purity	>98%

Roxithromycin-[13C,d3], a specialized antibiotic with isotopic labeling, is primarily utilized for research and analytical purposes. Here are key applications of Roxithromycin-[13C,d3] presented with high perplexity and burstiness:

Isotope Tracing Studies: Roxithromycin-[13C,d3] plays a pivotal role in isotope tracing studies aimed at unraveling the intricate metabolic pathways of antibiotics within biological systems. By meticulously tracking its labeled isotopes, researchers delve deep into the drug's absorption, distribution, metabolism, and excretion processes. This data is indispensable for deciphering pharmacokinetic profiles and honing dosing strategies to optimize therapeutic outcomes.

Pharmacokinetic Research: Within the realm of pharmacokinetics, Roxithromycin-[13C,d3] emerges as a valuable asset for investigating drug interactions and transport mechanisms. Researchers leverage this labeled compound to explore how Roxithromycin interacts with other medications and probe its affinity to various transport proteins.

Analytical Method Development: Roxithromycin-[13C,d3] finds its niche in the development and validation of cutting-edge analytical methods for quantifying Roxithromycin in complex samples. Its isotopic labeling facilitates the creation of highly sensitive mass spectrometry assays, ensuring precise and reliable measurements. These refined methods play a pivotal role in both clinical pharmacology studies and the quality control of pharmaceutical products, setting the standard for accuracy and precision in analytical workflows.

Environmental Monitoring: Delving into environmental studies, Roxithromycin-[13C,d3] assumes a crucial role in monitoring the presence and fate of antibiotics in environmental matrices such as water and soil. By harnessing this labeled compound, researchers track contamination sources and gauge the ecological repercussions of antibiotic residues in the environment. This data aids in evaluating the efficacy of wastewater treatment processes and devising strategic measures to mitigate environmental pollution, safeguarding ecological balance.