Lactose-[UL-13C12] monohydrate

Lactose-[UL-13C12] monohydrate is a labeled form of lactose where all 12 carbon atoms are enriched with the stable isotope 13C. This compound has several specialized applications in scientific research. Here are some key applications of Lactose-[UL-13C12] monohydrate:

Metabolic Flux Analysis: Lactose-[UL-13C12] monohydrate is used in metabolic flux analysis to study carbohydrate metabolism. By tracing the 13C-labeled atoms, researchers can determine the pathways and rates of lactose utilization in various organisms. This helps in understanding metabolic disorders and optimizing industrial fermentation processes.

Stable Isotope Labeling in NMR Studies: Lactose-[UL-13C12] monohydrate serves as an excellent substrate for Nuclear Magnetic Resonance (NMR) spectroscopy studies. The 13C label enhances the NMR signals, enabling detailed structural and dynamic analysis of lactose metabolism. This provides valuable insights into enzyme mechanisms and protein-carbohydrate interactions in biological systems.

Nutritional and Digestive Research: This isotope-labeled lactose variant is used to investigate lactose digestion and absorption in humans and animals. By tracking 13C-labeled lactose, researchers can study lactose intolerance and other digestive disorders. These studies help in developing better dietary strategies and therapeutic interventions for lactose malabsorption.

Pharmaceutical Development: Lactose-[UL-13C12] monohydrate is employed in the pharmaceutical industry for studying drug-lactose interactions and the stability of lactose-containing formulations. The 13C label allows for precise detection and quantification in complex matrices, facilitating the development of more stable and effective drug formulations.