D-Galactitol-[13C6]

D-Galactitol-[13C6] is a stable isotope-labeled compound used in a variety of scientific applications. Here are some key applications of D-Galactitol-[13C6]:

Metabolic Flux Analysis: D-Galactitol-[13C6] is utilized in metabolic flux analysis to track the flow of carbon through cellular metabolic pathways. By incorporating this labeled compound into cells, researchers can monitor how it is metabolized and map the dynamic changes in metabolic networks. This helps in understanding cellular metabolism and identifying potential metabolic bottlenecks.

Stable Isotope-Resolved Metabolomics: In metabolomics studies, D-Galactitol-[13C6] is employed as a tracer to profile metabolites and understand metabolic processes. It provides a non-invasive way to assess the incorporation and redistribution of carbon within biochemical pathways. This technique is critical for discovering biomarkers and elucidating disease mechanisms.

Biochemical Research: D-Galactitol-[13C6] is used in biochemical experiments to study enzyme activity and substrate utilization. By offering a precisely labeled substrate, researchers can quantify the kinetics and efficacy of enzyme-catalyzed reactions. This knowledge is crucial for developing enzyme inhibitors or activators for therapeutic purposes.

Pharmaceutical Development: In drug discovery and development, D-Galactitol-[13C6] is applied to study the pharmacokinetics and pharmacodynamics of new drug candidates. By following the labeled compound through different biological systems, scientists can gain insights into drug absorption, distribution, metabolism, and excretion. This information is vital for optimizing drug formulations and dosages.