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JWH-250 4-Hydroxypentyl metabolite-[d5] (indole-[d5])

General Information
Catalog: BLP-009657
Molecular Formula: C22H20D5NO3
Molecular Weight: 356.47
Chemical Structure
JWH-250 4-Hydroxypentyl metabolite-[d5] (indole-[d5])
Description An isotope labelled metabolite of JWH250. JWH250 is a synthetic cannabinoid which can activate both CB1 and CB2 receptors.
Synonyms 1-(1-(4-hydroxypentyl)-1H-indol-3-yl)-2-(2-methoxyphenyl)ethanone-2,4,5,6,7-d5
Related CAS 1427521-38-7 (unlabelled)
Purity 95% by HPLC; 98% atom D

Pharmacokinetic Studies: In the intricate field of pharmacokinetics, the utilization of JWH-250 4-Hydroxypentyl metabolite-[d5], a deuterated variant of JWH-250, a synthetic cannabinoid, serves as a valuable instrument for tracing the metabolic trajectory of JWH-250 within biological systems. The incorporation of deuterium atoms enables researchers to differentiate and quantitate this metabolite through meticulous mass spectrometry analysis, providing comprehensive insights into the absorption, distribution, metabolism, and excretion (ADME) profiles of the compound with unparalleled precision.

Forensic Toxicology: Within the domain of forensic toxicology, JWH-250 4-Hydroxypentyl metabolite-[d5] emerges as a pivotal internal standard for the detection and quantification of JWH-250 and its metabolites in biological samples. This critical role supports the screening of biological specimens from individuals suspected of synthetic cannabinoid consumption, bolstering legal procedures, and enhancing the efficacy of studies on drug abuse. Accurate quantification not only aids in legal proceedings but also fosters a deeper understanding of substance misuse.

Analytical Method Development: Playing a central role in the development of analytical methodologies, this compound serves as a cornerstone for crafting and validating techniques for the identification of synthetic cannabinoids and their metabolites. The deuterated nature of the metabolite enhances the precision and accuracy of chromatographic and mass spectrometric methods, establishing a robust framework for dependable analytical procedures in clinical and research environments.

Metabolomic Research: Venturing into the intriguing realm of metabolomics, JWH-250 4-Hydroxypentyl metabolite-[d5] emerges as a potent tool for exploring the broader metabolic impacts of synthetic cannabinoids. By examining metabolomic profiles in the presence of this deuterated metabolite, researchers can uncover insights into the biochemical pathways influenced by exposure to synthetic cannabinoids. This wealth of knowledge sheds light on the physiological and toxicological effects of these compounds, enriching our comprehension of their effects on biological systems.

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