D-mannose-[UL-13C6,UL-d7]

D-mannose-[UL-13C6,UL-d7], a universally labeled isotopic form of D-mannose, is highly valued in scientific applications for its stable isotope integration. Here are the key applications of D-mannose-[UL-13C6,UL-d7]:

Metabolic Flux Analysis: Delving into metabolic flux analysis, researchers utilize D-mannose-[UL-13C6,UL-d7] to trace the intricate pathways of mannose metabolism within cells. By closely monitoring the incorporation of this labeled mannose into metabolic compounds, scientists can quantitatively unravel and map the convoluted pathways of metabolism. This detailed analysis is vital for comprehending the dynamic nature of metabolic processes in various physiological and pathological contexts.

Glycoprotein Research: In the realm of glycoprotein studies, D-mannose-[UL-13C6,UL-d7] emerges as a pivotal tool for investigating intricate glycosylation processes. Incorporating this labeled mannose into glycoproteins allows for the meticulous tracking of glycan structures and their modifications. Researchers can glean profound insights into the multifaceted functions, degradation pathways, and signaling roles of glycoproteins in cellular communication and disease progression, unraveling the complexities of glycoprotein biology.

NMR and Mass Spectrometry: Equipped with stable isotopes, D-mannose-[UL-13C6,UL-d7] is uniquely suited for conducting detailed structural analyses using advanced techniques such as nuclear magnetic resonance (NMR) and mass spectrometry (MS). These sophisticated methodologies offer high-resolution insights into the molecular structures and interactions of mannose-containing biomolecules. This in-depth analysis aids in elucidating the intricate molecular mechanisms underlying carbohydrate-related biological processes, paving the way for a deeper understanding of the complexities of biomolecular interactions.

Nutritional Studies: In the realm of nutritional research, D-mannose-[UL-13C6,UL-d7] plays a crucial role in investigating the absorption, distribution, metabolism, and excretion (ADME) of mannose. By administering this labeled mannose and closely monitoring its metabolic fate, researchers can assess the efficiency of mannose utilization and its impact on overall health. This comprehensive approach is instrumental in shaping dietary strategies and unraveling the complexities of metabolic disorders associated with carbohydrate metabolism, shedding light on the intricate interplay between diet and physiological well-being.