Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-008975 |
Molecular Formula: C6[13C]6H22O11.H2O |
Molecular Weight: 366.27 |
Chemical Structure |
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Description | D-Lactose-[glucose-13C6] monohydrate is the labelled analogue of D-Lactose Monohydrate, which is used in the synthesis of casing for various methods of oral drug delivery, including dissolving pellets, and long-lasting pellets. |
Synonyms | [UL-13C6glc]lactose monohydrate; 4-O-β-D-galactopyranosyl-D-[UL-13C6]glucose |
IUPAC Name | (2S,3R,4R,5S,6R)-6-(hydroxymethyl-13C)-5-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2,3,4-triol-2,3,4,5,6-13C5 hydrate |
Related CAS | 64044-51-5 (unlabelled) |
Purity | 98% by CP; 98% atom 13C |
Storage | Store at -20°C |
D-Lactose-[glucose-13C6] monohydrate, a stable isotope-labeled compound, is a cornerstone in biochemical and metabolic research. Here are the key applications of D-Lactose-[glucose-13C6] monohydrate:
Metabolic Flux Analysis: A critical tool for tracing metabolic pathways and quantifying fluxes, this compound empowers researchers to meticulously monitor metabolite distribution and transformation employing cutting-edge techniques such as mass spectrometry and NMR spectroscopy. By introducing labeled D-Lactose into investigations, scientists unlock intricate insights into the dynamic interplay of metabolic networks illuminating pivotal regulatory nodes within the intricate landscape of biological systems.
Nutritional Studies: At the forefront of exploring carbohydrate digestion and metabolism, D-Lactose-[glucose-13C6] monohydrate serves as a key facilitator for assessing glucose absorption and utilization efficiency in both human and animal models. Researchers leverage this compound to scrutinize the effects of dietary interventions on digestive enzyme activity enabling the formulation of tailored nutritional strategies to address metabolic disorders like lactose intolerance amidst a backdrop of convoluted nutritional pathways.
Glycobiology Research: In the enchanting realm of glycobiology, this compound emerges as an indispensable tool for unraveling the mysteries of glycan biosynthesis and degradation. By meticulously tracking labeled glucose integration into glycoproteins and glycolipids, scientists embark on a journey to unravel the complexities of enzyme activities and pathway dynamics governing glycosylation processes. This voyage sheds light on diseases intertwined with glycan anomalies unveiling pathways for innovative glycan-centric therapies in a landscape adorned with enigmatic glycan structures.
Pharmaceutical Development: Pioneering advancements in pharmacokinetic studies, D-Lactose-[glucose-13C6] monohydrate serves as a catalyst for tracking the metabolism and distribution of lactose-containing drugs. Armed with the ability to monitor the fate of 13C-labeled glucose, researchers navigate the intricate terrain of drug absorption bioavailability and metabolic pathways crafting optimized formulations and dosing regimens for elevated efficacy and safety in clinical spheres where precision and optimization reign supreme.
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