Galpα1,3-[U-13C6]Galpβ1,4GlcpNAcα1-O-Bn

Galpα1,3-[U-13C6]Galpβ1,4GlcpNAcα1-O-Bn, a complex carbohydrate derivative, stands as a pivotal tool in the realm of glycoscience research. Here are the key applications of this compound:

Glycan Structure Elucidation: Delving into the intricate world of glycans, scientists utilize Galpα1,3-[U-13C6]Galpβ1,4GlcpNAcα1-O-Bn to unravel and unveil the complex structures of glycans. By introducing stable isotopes, researchers delve deep into the realm of advanced NMR and mass spectrometry techniques, meticulously detailing the architecture of glycans and pinpointing specific carbohydrate linkages. This knowledge is paramount in deciphering the significance of glycans in biological systems and the intricacies of disease pathology.

Metabolic Tracing Studies: Venturing into the domain of metabolic tracing studies, this labeled compound serves as a beacon to explore the enigmatic pathways of glycan biosynthesis. Researchers embark on a journey to track the assimilation and metamorphosis of the 13C-labeled sugars within cellular systems, shedding luminous insights on the labyrinthine realm of glycan metabolism and turnover. This intricate approach sheds light on cellular processes and unveils potential metabolic dysregulations entwined with various diseases.

Immunological Research: Within the expansive realm of immunological research, Galpα1,3-[U-13C6]Galpβ1,4GlcpNAcα1-O-Bn emerges as an indispensable tool for unraveling the mysteries of glycan-immune interactions. Acknowledging the pivotal roles glycans play in immune recognition and response, this compound serves as a beacon illuminating the binding affinities and specificities of immune cells or antibodies to distinct glycan structures. This knowledge acts as a cornerstone for the evolution of novel immunotherapies and vaccines, shaping the landscape of immunological advancements.

Glycoprotein Analysis: Transitioning to the crucial domain of glycoprotein analysis, researchers leverage this compound as both a standard and a probe in the exploration of glycoproteins. By integrating this labeled glycan into glycoprotein samples, scientists embark on a quest to identify and characterize the intricate glycosylation patterns that define these proteins. Such meticulous analysis serves as a linchpin in the realm of biopharmaceutical development, ensuring the steadfast consistency and efficacy of therapeutic proteins and sculpting the future of biopharmaceutical innovations.