Galpβ1,3Galpβ1,6([U-13C6]Galfβ1,4)GlcpNAc

Galpβ1,3Galpβ1,6([U-13C6]Galfβ1,4)GlcpNAc, a complex carbohydrate with diverse research and biotechnological applications, is utilized for a multitude of purposes. Here are the key applications of this carbohydrate:

Glycan Structure Analysis: Employed as a standard or reference material in glycan structure analysis, this complex oligosaccharide plays a pivotal role in calibrating mass spectrometry and chromatography systems for precise glycan profiling. By unraveling the intricate structures of glycoproteins and other glycoconjugates, researchers gain valuable insights into their biological functions, shedding light on the complexities of cellular interactions.

Metabolic Labeling: Facilitated by the [U-13C6] label, metabolic labeling studies in cells and organisms become possible through the use of this labeled carbohydrate. Scientists leverage this tool to track the incorporation and metabolism of sugars in biological systems, providing crucial information on glycosylation pathways and other biochemical processes involving carbohydrates, thereby unlocking the mysteries of cellular metabolism.

Glycosylation Pathways: Serving as a substrate or mimic for studying glycosylation pathways, both in vitro and in vivo, this oligosaccharide enables scientists to delve into the enzymatic processes underlying the assembly and modification of glycans. The insights garnered from these studies are instrumental in revealing the roles of glycosylation in maintaining health and combating disease, offering a deeper understanding of the intricate molecular mechanisms governing cellular functions.

Drug Development: Researchers harness the potential of this complex carbohydrate in exploring the interactions between glycan structures and glycan-binding proteins like lectins and antibodies, paving the way for the development of glycoconjugate vaccines and other therapeutic agents. This carbohydrate also plays a crucial role in the design and evaluation of glycan-based drugs targeting diverse diseases, offering promising avenues for novel treatment modalities in the realm of pharmaceutical innovation.