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L-Ascorbic Acid-[1,2-13C2]

General Information
Catalog: BLP-007081
Molecular Formula: C4[13C]2H8O6
Molecular Weight: 178.11
Chemical Structure
L-Ascorbic Acid-[1,2-13C2]
Description Labelled Ascorbic Acid. Physiological antioxidant. Coenzyme for a number of hydroxylation reactions; required for collagen synthesis. Widely distributed in plants and animals. Inadequate intake results in deficiency syndromes such as scurvy. Used as antimicrobial and antioxidant in foodstuffs.
Synonyms L-[1,2-13C2]ascorbic acid; L-Ascorbic Acid-1,2-13C2; [1,2-13C2]vitamin C; Vitamin C-1,2-13C2
Related CAS 50-81-7 (unlabelled)
Melting Point >187°C (dec.)
Purity 95%
Solubility Soluble in DMSO, Methanol, Water
Appearance White Solid
Storage Store at -20°C, Under inert atmosphere

L-Ascorbic Acid-[1,2-13C2], a carbon-labeled rendition of vitamin C, finds application in diverse bioscientific research endeavors. Here are the key applications:

Stable Isotope Tracing: In metabolic exploration, L-Ascorbic Acid-[1,2-13C2] emerges as a valuable tool for unraveling the intricate pathways of vitamin C within biological systems. By harnessing this labeled compound, researchers can meticulously trace the journey and metabolic transformations of ascorbic acid in cells and tissues. This technique plays an indispensable role in deciphering the contributions of vitamin C to cellular metabolism and antioxidative processes.

Nutritional Studies: Within the realm of nutritional examination, L-Ascorbic Acid-[1,2-13C2] serves as a key asset for quantifying and scrutinizing the absorption, bioavailability, and pharmacokinetics of vitamin C in both human and animal models. Through the administration of labeled vitamin C, scientists can precisely measure its uptake, distribution, and excretion utilizing mass spectrometry. These investigations offer pivotal insights into the intricate interplay between vitamin C, health, and disease prevention.

Oxidative Stress Research: Addressing the interplay between vitamin C and oxidative stress, L-Ascorbic Acid-[1,2-13C2] is instrumental in exploring the antioxidant prowess of the compound and its impacts on cellular well-being. Researchers delve into how labeled ascorbic acid interacts with free radicals and reactive oxygen species, both in vitro and in vivo settings, shedding light on the antioxidant attributes of vitamin C and its therapeutic potentials.

Biochemical Pathway Elucidation: Delving into the biochemical pathways concerning vitamin C, researchers utilize the labeled form of ascorbic acid to unravel the intricate networks of enzymatic reactions and intermediate compounds. By incorporating L-Ascorbic Acid-[1,2-13C2] into experimental setups, scientists can pinpoint specific steps within the vitamin C biosynthetic and catabolic pathways, fostering a holistic comprehension of how ascorbic acid functions at the molecular level.

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