Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-007082 |
Molecular Formula: C5[13C]H8O6 |
Molecular Weight: 177.12 |
Chemical Structure |
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Description | Labelled Ascorbic Acid. Physiological antioxidant. Coenzyme for a number of hydroxylation reactions; required for collagen synthesis. Widely distributed in plants and animals. Inadequate intake results in deficiency syndromes such as scurvy. Used as antimicrobial and antioxidant in foodstuffs. |
Synonyms | L-Ascorbic Acid-3-13C; Vitamin C-3-13C; L-[3-13C]ascorbic acid; [3-13C]vitamin C |
Related CAS | 50-81-7 (unlabelled) |
Purity | 97% |
Solubility | Soluble in DMSO, Methanol, Water |
Appearance | White to Off-White Solid |
Storage | Store at -20°C, Under inert atmosphere |
L-Ascorbic Acid-[3-13C], a compound enriched with the stable isotope carbon-13, finds wide application in scientific studies. Here are the key applications of L-Ascorbic Acid-[3-13C]:
Metabolic Tracing: Delving into metabolic pathways, researchers employ L-Ascorbic Acid-[3-13C] to unravel the intricate journey and turnover of ascorbic acid within biological systems. By scrutinizing the labeled compound's metabolic fate, valuable insights into the dynamics of vitamin C, encompassing absorption, distribution, and excretion, are gleaned. This knowledge plays a pivotal role in unraveling the significance of vitamin C in human health and disease.
Nutritional Research: In the realm of nutritional exploration, L-Ascorbic Acid-[3-13C] serves as a vital tool for assessing the bioavailability and effectiveness of dietary supplements. Researchers track the labeled vitamin C as it traverses through ingestion and metabolism in the body, shedding light on the performance of different vitamin C formulations and their impact on nutritional well-being. This application enhances understanding of how dietary supplements interact with the body's metabolic processes.
Pharmaceutical Development: In the pharmaceutical domain, L-Ascorbic Acid-[3-13C] plays a pivotal role in elucidating the pharmacokinetics and pharmacodynamics of vitamin C-based drugs. By leveraging the labeled compound, scientists unravel how these drugs are absorbed, distributed, metabolized, and excreted within the body. Such investigations are instrumental in fine-tuning drug formulations and dosage regimens, optimizing therapeutic outcomes.
Biological Research: Within the realm of biological inquiry, L-Ascorbic Acid-[3-13C] serves as a valuable asset for exploring the multifaceted role of vitamin C in cellular processes like antioxidant defense and collagen synthesis. The isotopic labeling enables precise quantification of vitamin C integration and functionality within cells, facilitating a deeper understanding of how vitamin C influences cellular activities and overall health. This application aids in unraveling the intricate molecular mechanisms underpinning the beneficial effects of vitamin C on cellular function.
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