2-Amino-2-deoxy-D-glucose-[6-13C] hydrochloride

2-amino-2-deoxy-D-glucose-[6-13C] hydrochloride, a labeled glucose analog, holds widespread utility in biochemical and medical research. Here we explore the key applications of this compound:

Cancer Metabolism Studies: Delving into the intricacies of cancer biology, researchers employ 2-amino-2-deoxy-D-glucose-[6-13C] hydrochloride to unravel the aberrant glucose metabolism in malignant cells. By tracing the labeled carbon atom's journey, scientists track glycolytic pathways, shedding light on how cancer cells rewire their energy production mechanisms. This knowledge is paramount for crafting metabolic-driven therapeutic interventions that combat cancer at its metabolic core.

Glycoprotein Biosynthesis Research: At the forefront of glycoprotein studies, 2-amino-2-deoxy-D-glucose-[6-13C] hydrochloride emerges as a pivotal tool for dissecting glycan biosynthesis processes. By integrating into glycans, researchers trace and scrutinize glycan assembly dynamics, unveiling insights into cell surface interactions and paving the way for precision-targeted therapies that manipulate these crucial molecular interactions.

Mitochondrial Function Assessment: Offering a window into mitochondrial biology, this glucose analog is applied to evaluate mitochondrial function and glucose metabolism dynamics. Through the incorporation of 2-amino-2-deoxy-D-glucose-[6-13C] hydrochloride into metabolic assessments, researchers track its uptake and subsequent metabolic destiny, offering crucial insights into mitochondrial dysfunction across various disease states and enriching our understanding of cellular energetics.

NMR-Based Metabolomics: In the realm of nuclear magnetic resonance (NMR) metabolomics, the labeled glucose analog serves as a cornerstone for identifying and quantifying metabolic intermediates within complex biological matrices. Facilitating a comprehensive metabolic snapshot, this tool aids in unraveling intricate metabolic networks and pinpointing potential biomarkers for diverse disease contexts, contributing to the advancement of personalized medicine and diagnostic precision.