D-Mannose-[6-18O]

D-Mannose-[6-18O], an isotopically labeled carbohydrate with diverse scientific uses, presents numerous applications for research endeavors. Here are the key applications of D-Mannose-[6-18O], articulated:

Metabolic Tracing: Delving into the intricate realm of carbohydrate metabolism, D-Mannose-[6-18O] serves as a valuable tracer for unraveling metabolic pathways within biological systems. By introducing this labeled mannose into metabolic cascades, researchers are able to trace the intricate flow and transformation of sugars through diverse biochemical reactions. This methodology aids in comprehending the complexities of metabolic networks and elucidating the pivotal role of mannose in various cellular processes.

Glycoprotein Research: In the exploration of glycoprotein biosynthesis and structure, scientists leverage D-Mannose-[6-18O] as a crucial tool. Through the incorporation of labeled mannose into glycan chains of glycoproteins, researchers gain insights into the formation and remodeling of these essential biomolecules. This application plays a pivotal role in unraveling the nuances of protein folding, stability, and deciphering intricate cellular signaling mechanisms.

Mass Spectrometry: A cornerstone in mass spectrometry-based analyses, D-Mannose-[6-18O] offers unparalleled utility. By utilizing this isotopically labeled compound, researchers can discern between various isotopes of mannose in mass spectrometric investigations. This capability enhances the precision and dependability of quantitative analyses in the realm of biomolecular research, facilitating the exploration of complex biological phenomena.

Drug Development: In the domain of pharmaceutical research, D-Mannose-[6-18O] emerges as a versatile asset for probing the pharmacokinetics and metabolism of mannose-containing drugs. Understanding the absorption, distribution, metabolism, and excretion dynamics of these drugs can provide valuable insights for designing more efficacious therapeutic agents. This application holds particular relevance in the development of drugs targeting metabolic disorders and infectious diseases, paving the way for enhanced treatment modalities.