Galpβ1,2Galpβ1,6([U-13C6]Galpβ1,4)GlcpNAc

Galpβ1,2Galpβ1,6([U-13C6]Galpβ1,4)GlcpNAc, a complex carbohydrate structure with detailed labeled isotopic composition, finds diverse applications in scientific and industrial realms. Here are the key applications of Galpβ1,2Galpβ1,6([U-13C6]Galpβ1,4)GlcpNAc:

Glycomics Research: This labeled oligosaccharide plays a pivotal role in glycomics research, where scientists delve into the intricate structures and functions of complex carbohydrates in biological systems. The isotopic label ([U-13C6]Galp) facilitates precise tracking and quantitation in mass spectrometry studies, enabling researchers to explore carbohydrate metabolism and glycan interactions within cells in a nuanced manner.

Structural Biology: Within the realm of structural biology, Galpβ1,2Galpβ1,6([U-13C6]Galpβ1,4)GlcpNAc serves as a key tool in unraveling the three-dimensional structures of glycoproteins and glycan-bearing molecules. By incorporating this labeled oligosaccharide into glycoproteins, scientists enhance the accuracy of NMR and X-ray crystallography studies. This advancement aids in deepening the understanding of the structural underpinnings of glycan-mediated biological functions, advancing structural biology discoveries.

Biotechnological Applications: This intricate carbohydrate structure finds utility in various biotechnological applications, including the development of novel biosensors and diagnostic tools. Its specific isotopic labeling boosts detection sensitivity in assays, facilitating enhanced precision in scientific investigations. For example, it plays a crucial role in creating labeled standards for quantitative analysis in glycoengineering studies, pushing the boundaries of biotechnological innovation.

Pharmaceutical Development: In the landscape of pharmaceutical research, Galpβ1,2Galpβ1,6([U-13C6]Galpβ1,4)GlcpNAc emerges as a valuable asset for designing and evaluating glycan-based therapeutics. The isotopic labeling aids researchers in monitoring the metabolism and bio-distribution of therapeutic glycans, which is crucial for optimizing the efficacy and safety profiles of glycan-targeted drugs. This information is essential for refining pharmaceutical interventions and advancing the field of pharmaceutical development.