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Artemether-[13C,d3]

General Information
Catalog: BLP-012804
CAS: 71963-77-4
Molecular Formula: C15[13C]H23D3O5
Molecular Weight: 302.39
Chemical Structure
Artemether-[13C,d3]
Description Artemether-[13C,d3] is the labelled analogue of Artemether. Artemether is an antimalarial for the treatment of multiple drug-resistant strains of Plasmodium falciparum malaria.
Synonyms Artemether 13C D3; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-13C,d3; Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-13C,d3; Artemos-13C,d3; Artenam-13C,d3; Artesaph-13C,d3; Artesian-13C,d3; Dihydroartemisinin Methyl Ether-13C,d3; Falcidol-13C,d3; Gvither-13C,d3; Larither-13C,d3; Malartem-13C,d3; β-Artemether-13C,d3; β-Dihydroartemisinin Methyl Ether-13C,d3
IUPAC Name (1R,4S,5R,8S,9R,10S,12R,13R)-1,5,9-trimethyl-10-(trideuterio(1-13C)methoxy)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane
Related CAS 71963-77-4 (unlabelled)
Canonical SMILES CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC)C
InChI InChI=1S/C16H26O5/c1-9-5-6-12-10(2)13(17-4)18-14-16(12)11(9)7-8-15(3,19-14)20-21-16/h9-14H,5-8H2,1-4H3/t9-,10-,11+,12+,13+,14-,15-,16-/m1/s1/i4+1D3
InChI Key SXYIRMFQILZOAM-QJQJLBRWSA-N
Melting Point 87 - 89°C
Purity 95% by HPLC; 98% atom 13C; 98% atom D
Solubility Soluble in Chloroform (Slightly), Methanol (Slightly)
Appearance White to Off-white Solid
Storage Store at 2-8°C

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